CYTOLOGIC APPEARANCES OF PHEOCHROMOCYTOMA AND MEDULLARY-THYROID CARCINOMA OCCURRING WITHIN A FAMILY
- 1 January 1978
- journal article
- research article
- Vol. 22 (5) , 321-326
Abstract
The cytologic and histochemical characteristics of the tumor cells from medullary thyroid carcinoma and pheochromocytoma are described. In cell samples obtained from medullar thyroid carcinomas, amyloid deposits were detected both intracellularly and extracellularly. Medullary thyroid carcinoma cells, as well as pheochromocytoma cells, showed positive for both argentaffin and argyrophil reactions. The diagnostic significance of intraccelular amyloid deposits and of positive Ag and chromaffin reactions of the intracytoplasmic granules may be stressed in establishing the cytologic diagnosis of medullary thyroid carcinoma and/or pheochromocytoma.This publication has 4 references indexed in Scilit:
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- Familial Amyloid-producing Medullary Thyroid Carcinoma and PheochromocytomaAnnals of Internal Medicine, 1965
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- HISTOCHEMICAL DEMONSTRATION OF NORADRENALINE AND ADRENALINE IN THE ADRENAL MEDULLAJournal of Histochemistry & Cytochemistry, 1955