Effect of LRH on Gonadotropin Secretion in Newborn Male Infants

Abstract
The concentrations of LH and FSH were measured in eight male newborn babies, aged 4–6 h, before and after the administration of 25 μg synthetic LHR. A comparison was performed with six control newborns receiving normal saline. Both LH and FSH rose significantly in all subjects after LHR administration.Their values were significantly higher than those observed during the control study. These data demonstrate sensitivity of the pituitary gonadotropes to synthetic LHR and a pubertal-type response of LH in the early hours of human life.

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