Abstract
Xenopus laevis were kept in salt water (1.25% NaCl), distilled water, or tapwater for a month. Compared to the animals kept in tap water, the number of mitochondria‐rich (MR) cells in the NaCl‐adapted animals was significantly reduced, while it was increased in those maintained in distilled water. In addition, the MR‐cells of NaCl‐adapted animals lost their slender flask shape and developed large deposits of glycogen. The alteration of this cell type in conditions of high or low salinity may reflect a role of MR‐cells in adaptation to different ionic environments.