Predictors of Remission in Juvenile-Onset Recurrent Respiratory Papillomatosis

Abstract
JUVENILE-ONSET recurrent respiratory papillomatosis (JORRP) is a rare chronic disease that is diagnosed between birth and adolescence and caused by infection with human papillomavirus (HPV).1 Repeated growth of papillomas or benign tumors, usually in the larynx and upper respiratory tract, characterizes JORRP and may obstruct the airway, causing hoarseness, difficulty in breathing, abnormal cry, or voice change.2,3 Approximately 1500 to 2000 new cases occur annually in the United States.3-5 Although rare, JORRP results in substantial childhood morbidity.2