Blockade of Vascular Endothelial Cell Growth Factor Receptor Signaling Is Sufficient to Completely Prevent Retinal Neovascularization
- 1 February 2000
- journal article
- Published by Elsevier in The American Journal of Pathology
- Vol. 156 (2) , 697-707
- https://doi.org/10.1016/s0002-9440(10)64773-6
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.2000
- Dramatic Inhibition of Retinal and Choroidal Neovascularization by Oral Administration of a Kinase InhibitorThe American Journal of Pathology, 1999
- Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors.1998
- Inhibition of platelet‐derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferationThe FASEB Journal, 1997
- Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization.1997
- Essential Role of Growth Hormone in Ischemia-Induced Retinal NeovascularizationScience, 1997
- Antagonists of integrin alpha v beta 3 inhibit retinal neovascularization in a murine model.1996
- Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy.Proceedings of the National Academy of Sciences, 1996
- Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor–type integrins inhibits retinal neovascularizationNature Medicine, 1996
- Inhibition of Vascular Endothelial Growth Factor Prevents Retinal Ischemia—Associated Iris Neovascularization in a Nonhuman PrimateArchives of Ophthalmology (1950), 1996