Guanylate cyclase activity in normal and diseased human muscle.
- 1 September 1978
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 41 (9) , 805-808
- https://doi.org/10.1136/jnnp.41.9.805
Abstract
Guanylate cyclase activity was studied in muscle of normal subjects and of patients suffering from muscular and neuromuscular diseases. In normal tissue a guanylate cyclase activity was found in both soluble and particulate fractions of homogenate. The kinetic analysis of the enzyme of soluble apparently differed from that of particulate fraction. A decrease of guanylate cyclase activity in crude homogenate was observed in muscular dystrophies, in neuromuscular atrophies and in inflammatory forms of muscle disease.Keywords
This publication has 23 references indexed in Scilit:
- Adenylate cyclase and guanylate cyclase of normal and denervated skeletal muscleNeurology, 1977
- Guanylate cyclase. Subcellular distribution in cardiac muscle, skeletal muscle, cerebral cortex and liverBiochemical Journal, 1976
- The role of cyclic AMP in myogenesisJournal of Cellular Physiology, 1975
- The possible role of cyclic AMP in the neurotrophic control of skeletal muscle.The Journal of Physiology, 1975
- Cyclic AMP and Cyclic GMP May Mediate Opposite Neuronal Responses in the Rat Cerebral CortexScience, 1975
- Adenyl cyclase activity in Duchenne dystrophic muscleJournal of the Neurological Sciences, 1975
- Adenyl Cyclase in Normal and Pathologic Human MuscleArchives of Neurology, 1974
- The Role of Cyclic 3', 5'-Adenosine Monophosphate in Neuromuscular TransmissionArchives of Neurology, 1973
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951
- The Determination of Enzyme Dissociation ConstantsJournal of the American Chemical Society, 1934