SODIUM NITROPRUSSIDE-INDUCED HYPOTENSION IN RADICAL THORACO-ABDOMINAL DISSECTION OF RETROPERITONEAL LYMPH NODES

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Abstract
Blood loss and replacement in 57 consecutive otherwise healthy young patients undergoing radical thoraco-abdominal dissection of retroperitoneal lymph nodes is reviewed. Twenty-five patients received nitroprusside (hypotensive group); 32 patients (normotensive group) did not. Blood loss varied significantly between the hypotensive and normotensive groups: the mean loss (± SEM) was 920 ±72 ml for the hypotensive group compared with 1341 ± 98 ml for the normotensive group (P<0.001). The total blood requirement for the normotensive patients was three times that of the hypotensive group. The difference between the two groups was more apparent in patients with advanced disease.

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