Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co‐inducibility during iron overload1
Open Access
- 8 April 2003
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 542 (1-3) , 22-26
- https://doi.org/10.1016/s0014-5793(03)00329-6
Abstract
In contrast to the human genome, the mouse genome contains two HEPC genes encoding hepcidin, a key regulator of iron homeostasis. Here we report a comparative analysis of sequence, genomic structure,...Keywords
This publication has 22 references indexed in Scilit:
- Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosisNature Genetics, 2002
- Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic diseaseBlood, 2002
- C/EBPα Regulates Hepatic Transcription of Hepcidin, an Antimicrobial Peptide and Regulator of Iron MetabolismJournal of Biological Chemistry, 2002
- The Solution Structure of Human Hepcidin, a Peptide Hormone with Antimicrobial Activity That Is Involved in Iron Uptake and Hereditary HemochromatosisJournal of Biological Chemistry, 2002
- A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron OverloadJournal of Biological Chemistry, 2001
- Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the LiverJournal of Biological Chemistry, 2001
- Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosisProceedings of the National Academy of Sciences, 2001
- The hypotransferrinaemic mouse: Ultrastructural and laser microprobe analysis observationsThe Journal of Pathology, 1995
- The mouse intracisternal A particle-promoted placental gene retrotransposition is mouse-strain-specific.Proceedings of the National Academy of Sciences, 1993
- Ultrastructural observations in the carbonyl iron-fed rat, an animal model for hemochromatosisVirchows Archiv B Cell Pathology Including Molecular Pathology, 1987