Quantitative Enzyme Studies in Extensor Digitorum Longus and Soleus Muscles of Rats

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Abstract
The activities of eleven enzymes have been studied quantitatively in the extensor digitorum longus and soleus muscles of rats. Creatine kinase, adenylate kinase, AMP-deaminase, phosphorylase and acid cathepsin were found to have higher specific activities in EDL than SOL. Succinate-INT reductase was found to have the same specific activity in both muscles. Glutamate dehydrogenase, acid a-glucosidase, acid and neutral ribonucléase, and alkaline cathepsin were found to have higher specific activities in SOL than EDL. These findings are discussed with reference to what is known of the physiological roles and subcellular distributions of these enzymes, and with reference to alterations in muscle enzyme activities in muscular dystrophy.

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