Deoxyribonucleic acid methylation in mycobacteria
- 1 November 1981
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 148 (2) , 716-719
- https://doi.org/10.1128/jb.148.2.716-719.1981
Abstract
Deoxyribonucleic acid modification in six strains of mycobacteria was investigated. The presence of 5-methylcytosine in the virulent strain Mycobacterium tuberculosis H37Rv and its absence in the avirulent strain M. tuberculosis H37Ra and other saprophytic, fast-growing mycobacteria appear to be the salient features. However, deoxyribonucleic acid from M. smegmatis SN2 lysogenized with the temperature phage I3 showed the presence of 5-methylcytosine. All of the strains had N6-methyladenine.This publication has 15 references indexed in Scilit:
- DETERMINATION OF GENOME SIZE AND BASE RATIO ON DEOXYRIBONUCLEIC ACID FROM MYCOBACTERIAActa Pathologica Microbiologica Scandinavica Section B Microbiology, 1978
- Modified bases in the DNAs of unicellular eukaryotes: an examination of distributions and possible roles, with emphasis on hydroxymethyluracil in dinoflagellatesBiosystems, 1978
- Intermediary metabolism of mycobacteria.1972
- Methylation of Cytosine Residues in DNA Controlled by a Drug Resistance FactorProceedings of the National Academy of Sciences, 1972
- Corynebacterium diphtheriae and its relatives.1970
- Transduction in Mycobacterium smegmatisNature, 1970
- 5-Methylcytosine and 6-Methylaminopurine in Bacterial DNANature, 1968
- The occurrence of 6-methylaminopurine in deoxyribonucleic acidsBiochemical Journal, 1958
- Occurrence of 5-Methyl-Cytosine in Nucleic AcidsNature, 1950
- RESEARCHES ON PYRIMIDINES. C111. THE DISCOVERY OF 5-METHYL-CYTOSINE IN TUBERCULINIC ACID, THE NUCLEIC ACID OF THE TUBERCLE BACILLUS1Journal of the American Chemical Society, 1925