Comparison of aortic and carotid chemoreceptor responses to hypercapnia and hypoxia
- 1 July 1981
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 51 (1) , 55-61
- https://doi.org/10.1152/jappl.1981.51.1.55
Abstract
A quantitative comparison of the responses between aortic and carotid chemoreceptors to steady-state levels of arterial CO2 and O2 partial pressure was made in 35 cats anesthetized, paralyzed and artificially ventilated. The measurements on the 2 receptors were made simultaneously in 6 cats and separately in 29 cats. The response of aortic chemoreceptors to a CO2 stimulus was a fraction of that of carotid chemoreceptors and the response to hypoxia was relatively blunted. The differences between the 2 chemoreceptors are quantitative rather than qualitative. Since a low arterial CO2 partial pressure stimulus attenuates the hypoxic response of carotid chemoreceptors, the low CO2 response of aortic body chemoreceptors may be responsible for their blunted hypoxic response.This publication has 8 references indexed in Scilit:
- Relative responses of aortic body and carotid body chemoreceptors to carboxyhemoglobinemiaJournal of Applied Physiology, 1981
- Relative responses of aortic body and carotid body chemoreceptors to hypotensionJournal of Applied Physiology, 1980
- Relative latency of responses of chemoreceptor afferents from aortic and carotid bodiesJournal of Applied Physiology, 1980
- Aortic body chemoreceptor responses to changes in PCO2 and PO2 in the catJournal of Applied Physiology, 1979
- Arterial PO2 and PCO2 stimulus threshold for carotid chemoreceptors and breathingRespiration Physiology, 1978
- Anemia as a stimulus to aortic and carotid chemoreceptors in the catJournal of Applied Physiology, 1978
- Responses of aortic chemoreceptors.Journal of Applied Physiology, 1966
- Specificity of H ion concentration as a carotid chemoreceptor stimulusJournal of Applied Physiology, 1963