Advances in the design and therapeutic use of capsaicin receptor TRPV1 agonists and antagonists
- 22 February 2008
- journal article
- Published by Taylor & Francis in Expert Opinion on Therapeutic Patents
- Vol. 18 (2) , 159-209
- https://doi.org/10.1517/13543776.18.2.159
Abstract
(2008). Advances in the design and therapeutic use of capsaicin receptor TRPV1 agonists and antagonists. Expert Opinion on Therapeutic Patents: Vol. 18, No. 2, pp. 159-209. doi: 10.1517/13543776.18.2.159Keywords
This publication has 79 references indexed in Scilit:
- A local route to pain reliefNature, 2007
- Developments in the pharmacotherapy of the overactive bladderCurrent Opinion in Urology, 2007
- Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathyBMC Neurology, 2007
- The TRPV1 receptor and nociceptionSeminars in Cell & Developmental Biology, 2006
- Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivoBiochemical and Biophysical Research Communications, 2006
- Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazolesJournal of Medicinal Chemistry, 2006
- Development of the First Ultra-Potent “Capsaicinoid” Agonist at Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channels and Its Therapeutic PotentialThe Journal of Pharmacology and Experimental Therapeutics, 2005
- Cloning and pharmacological characterization of mouse TRPV1Neuroscience Letters, 2004
- The VR1 Antagonist Capsazepine Reverses Mechanical Hyperalgesia in Models of Inflammatory and Neuropathic PainThe Journal of Pharmacology and Experimental Therapeutics, 2003
- The influence of local capsaicin treatment on small nerve fibre function and neurovascular control in symptomatic diabetic neuropathyActa Diabetologica, 2002