Reduced sensitivity of F-1 hybrid rats to re-challenge with parental strain spleen cells.
- 1 April 1966
- journal article
- Vol. 1 (2) , 195-205
Abstract
1. F1 hybrid rats that recovered from graft-versus-host (GVH) disease induced by the intraperitoneal injection of spleen cells of one parental strain showed varying degrees of resistance on re-challenge with cells of the same or of the other parental strain. Resistance to re-challenge, expressed either in terms of mortality or of severity of clinical manifestations, was greater after a strong than after a weak response to first challenge.This publication has 20 references indexed in Scilit:
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