Abstract
The studies of Dobell (1931), Kessel (1928), and others established the fact that the “histolytica-like” amebae found in monkeys are identical with E. histolytica in man. While it has been shown by many investigators that this parasite can be transmitted to a wide variety of hosts, in none of these can the infection be considered a normal one. Thus, dogs, kittens, rats, pigs, rabbits, guinea pigs and even chicks have been infected experimentally with E. histolytica. But in such cases infection is usually achieved only under special conditions. Also, the regular production of cysts is rarely seen, and it seems logical to assume that cyst-production here is good evidence of a normal host-parasite relationship For a proper understanding of the host-parasite relationships of E. histolytica the parasite must be studied in its normal host.