Nitration of 3-acylindoles in the presence of metal MeCN solvates and synthesis of the antibiotic alkaloid chuangxinmycin.
- 31 December 1986
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 35 (7) , 2656-2660
- https://doi.org/10.1248/cpb.35.2656
Abstract
Nitration of 3-acylindoles in the presence of MeCN solvates of Cu2+, Al3+, and Fe2+ salts yielded 3-nitroindole, 4-nitro- and 6-nitro-3-acylindoles, of which 3-acetyl-4-nitroindole was subsequently transformed into dehydrochuangxinmycin (7), the dehydro derivative of the antibiotic alkaloid chuangxinmycin (2).This publication has 0 references indexed in Scilit: