INVESTIGATION OF THE PRESENCE OF CHROMAFFIN CELLS IN THE UTERUS OF THE MOUSE

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Abstract
This investigation stems from two papers by Rudzik & Miller (1962a, b) on the mechanism by which relaxin effects uterine myometrial inhibition. From the results of experiments in vitro, the authors concluded that, in the rat, the uterine inhibitory action of relaxin is mediated indirectly through the release of catecholamines, mainly adrenaline. Relaxin also inhibits uterine contractions in the mouse. A number of experiments on the mouse uterus in vitro have been carried out in this laboratory by Mr P. A. Judd (unpublished). Although more work needs to be done before Rudzik & Miller's hypothesis can be accepted for this species, the preliminary results are, in the main, similar to those reported for the rat. The experiments of Rudzik & Miller give no clue to the site of storage and release of adrenaline in the uterus, but the authors point out that Adams-Ray, Nordenstam & Rhodin (1958) reported the

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