Artificial Elimination of Drug Resistance from Group A Beta-Hemolytic Streptococci
Open Access
- 1 May 1975
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 7 (5) , 719-720
- https://doi.org/10.1128/aac.7.5.719
Abstract
Ten strains of beta-hemolytic streptococci were tested for elimination of resistance to macrolide antibiotics, tetracycline, and chloramphenicol. Six of the strains lost resistance after cultivation at 41 C or addition of acriflavine (0.2 μg/ml). These results suggest that determinants governing resistance to these antibiotics are located on extrachromosomal genetic elements (plasmids) that are widely distributed in streptococci.Keywords
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