Phenylazothioformamide, the active principle in the fungitoxic action of 1‐phenylthiosemicarbazide
- 1 June 1968
- journal article
- research article
- Published by Wiley in Annals of Applied Biology
- Vol. 61 (3) , 473-479
- https://doi.org/10.1111/j.1744-7348.1968.tb04549.x
Abstract
SUMMARY: Laboratory trials using Aspergillus niger indicate that the antifungal effect of 1‐phenylthiosemicarbazide is based upon its conversion into an oxidation product, phenylazothioformamide. This conversion takes place much more slowly at pH 5 than at pH 7 and is completely prevented by the reducing agent sodium thioglycollate. Both acidity of the medium and the presence of reducing agents lower the fungitoxicity of 1‐phenylthiosemicarbazide.This publication has 2 references indexed in Scilit:
- Oxidation products of 1‐phenylthiosemicarbazides and their antifungal activityRecueil des Travaux Chimiques des Pays-Bas, 1968
- The antifungal activity of thiosemicarbazides in vitro and their systemic activity against cucumber scab Cladosporium cucumerinumAnnals of Applied Biology, 1966