Comparison of two elective transfer policies of two embryos to reduce multiple pregnancies without impairing pregnancy rates.
Open Access
- 1 January 1999
- journal article
- research article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 14 (1) , 83-89
- https://doi.org/10.1093/humrep/14.1.83
Abstract
A first elective transfer policy of two embryos based solely on embryo morphology was compared to a more restrictive policy transferring two embryos to all patients aged P < 0.05). Of 99 pregnancies, only 24.2% were multiple including 1% of triplets compared to 40.7% multiple pregnancies including 6.7% of triplets for the first policy. Forty-eight transfers of two average embryos with the new policy were compared to 264 transfers of three average embryos with the old policy. Multiple pregnancy rates per transfer were significantly reduced by a third from 23 to 8% (P < 0.05) without a reduction of the pregnancy rates (42 and 48%). This study demonstrated that elective transfer of two embryos reduced the number of multiple pregnancies without impairing the pregnancy rates even with the transfer of average embryos.Keywords
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