A Quantitative Chromatographic Method for the Determination of Purity of Griseofulvin
- 1 December 1963
- journal article
- abstracts
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 15 (Supplement) , 274T-277T
- https://doi.org/10.1111/j.2042-7158.1963.tb11223.x
Abstract
A chromatographic assay for the determination of griseofulvin is described, employing a hexane: methanol: chloroform: water partition system supported on Celite. Chromatographic separation is followed by ultra-violet measurement of the eluate fractions at 291 mμ. The system enables the determination of griseofulvin to be made in the presence of tetrahydrogriseofulvin, dehydrogriseofulvin, dihydrogriseofulvin, isogriseofulvin, dechlorogriseofulvin and griseofulvic acid.Keywords
This publication has 0 references indexed in Scilit: