Drug-induced changes in the plasma membrane of Microsporum canis.
- 1 May 1977
- journal article
- research article
- Published by Wiley in British Journal of Dermatology
- Vol. 96 (5) , 515-520
- https://doi.org/10.1111/j.1365-2133.1977.tb07155.x
Abstract
Commercial solutions of clotrimazole, tolnaftate and tolcyclate were tested for 12 h in cultures of M. canis. They induced modifications in particle distribution, a blebbing of particle-free areas and the appearance of lamellar figures on the plasma membrane of fungus cells. The 1st 2 changes in the plasma membrane might be ascribed to a modification of the spectrin-like meshwork, while the 3rd could be the result of a crystalline organization of membrane lipids.This publication has 11 references indexed in Scilit:
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