THE EXCRETION OF SPECIFIC FLUORESCENT SUBSTANCES IN THE URINE IN EXPERIMENTAL NICOTINIC ACID DEFICIENCY 12
Open Access
- 1 May 1942
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 21 (3) , 263-267
- https://doi.org/10.1172/jci101298
Abstract
The fluorescent substances F1 and F2 occur in the urine of dogs with exptl. nicotinic acid deficiency. Observations on these animals are in agreement with those made in human pellagra, that acute nicotinic acid deficiency is characterized by the disappearance of F2 excretion and a rise in F1 excretion. As the disease becomes more chronic, the excretion of F1 likewise tends to fall. The effect of nieotinic acid in reversing these changes is illustrated.This publication has 2 references indexed in Scilit:
- THE CLINICAL MANIFESTATIONS OF NICOTINIC ACID AND RIBOFLAVIN DEFICIENCY (PELLAGRA)Annals of Internal Medicine, 1941
- THE EXCRETION OF SPECIFIC FLUORESCENT SUBSTANCES IN THE URINE IN PELLAGRAScience, 1941