Functional diversity of helper T lymphocytes
- 31 October 1996
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 383 (6603) , 787-793
- https://doi.org/10.1038/383787a0
Abstract
The existence of subsets of CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity of normal and pathological immune responses. Defining the cellular and molecular mechanisms of helper-T-cell differentiation should lead to rational strategies for manipulating immune responses for prophylaxis and therapy.Keywords
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