Alkylating γ-Lactone-Opening: A Short Synthesis of Benzyl 3-O-Benzyl-1,2-O-isopropylidene-α-D-glucofuranuronate
- 1 July 1989
- journal article
- research article
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 8 (3) , 443-455
- https://doi.org/10.1080/07328308908048573
Abstract
γ-Lactones were reacted with barium oxide/barium hydroxide/benzyl bromide in dimethylformamide to result in simultaneous benzylation of the γ-hydroxyl group and esterification of the carboxylic acid. A suitable protecting group for an α-hydroxyl function proved to be the tetrahydropyranyl group. The title compound was thus obtained in four steps from D-glucurono-6, 3-lactone.This publication has 10 references indexed in Scilit:
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