Prevalence of Antibodies to Nucleic Acids in Insulin-dependent Diabetics and Their Relatives
Open Access
- 1 October 1981
- journal article
- research article
- Published by American Diabetes Association in Diabetes
- Vol. 30 (10) , 873-874
- https://doi.org/10.2337/diab.30.10.873
Abstract
We have studied nucleic acid antibodies in 23 insulindependent diabetics, 27 of their first degree relatives, and 23 normal, unrelated controls. We have found a significantly increased prevalence of antibody to ss-DNA, ds-RNA (reovirus), and synthetic RNA (Poly A · Poly U, Poly I · Poly C) in the unaffected relatives as well as in the diabetics when compared with normal controls. There was no relationship in HLA.Keywords
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