ON-LINE P o 2 AND P N 2 o ANALYSIS WITH AN IN VIVO CATHETER ELECTRODE

Abstract
A technique was developed for the in vivo determination of Po2 and PN2o with a catheter electrode using double-pulse polarography. The method was evaluated in dog studies comparing readings from the electrode with those from a mass spectrometer employing an in vivo probe. The oxygen readings obtained from the catheter electrode were also compared with values obtained by conventional blood-gas analysis. Good agreement was observed between the electrode and the mass spectrometer for both Po2 and PN2o. Similar agreement was found between the electrode readings and blood-gas analysis for Po2. In the presence of halothane, the electrode over-read for both Po2 and PN2O; a remedy is suggested. The in vivo electrode provides an effective, less expensive, alternative to the mass spectrometer for the on-line measurement of Po2, and PN2o in vivo.

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