SDR grafting of a murine antibody using multiple human germline templates to minimize its immunogenicity
- 31 July 2004
- journal article
- Published by Elsevier in Molecular Immunology
- Vol. 41 (9) , 863-872
- https://doi.org/10.1016/j.molimm.2004.03.041
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- A Combinatorial Library Strategy for the Rapid Humanization of Anticarcinoma BR96 FabJournal of Biological Chemistry, 1996
- A directory of human germ‐line Vχ segments reveals a strong bias in their usageEuropean Journal of Immunology, 1994
- Anatomy of the antibody moleculeMolecular Immunology, 1994
- Humanization of 60.3, an anti-CD18 antibody; importance of the L2 loopProtein Engineering, Design and Selection, 1994
- The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loopsJournal of Molecular Biology, 1992
- A general method for rapid site-directed mutagenesis using the polymerase chain reactionGene, 1990
- Serologic mapping and biochemical characterization of the carcinoembryonic antigen epitopes using fourteen distinct monoclonal antibodiesInternational Journal of Cancer, 1989
- Replacing the complementarity-determining regions in a human antibody with those from a mouseNature, 1986
- The rapid determination of binding constants for antiviral antibodies by a radioimmunoassay. An analysis of the interaction between hybridoma proteins and influenza virusMolecular Immunology, 1979
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976