Nucleotide sequence analysis of a region of adenovirus 5 DNA encoding a hitherto unidentified gene
Open Access
- 1 January 1980
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 8 (24) , 6033-6042
- https://doi.org/10.1093/nar/8.24.6033
Abstract
The nucleotide sequence of a region located on the adenovirus type 5 genome between coordinates 59.9 and 62.5 has been determined. This region comprises the 3′-termini of mRNAs coding for the hexon and the DNA binding protein. The sequence reveals the presence of an open reading frame in r-strand transcripts downstream from the hexon termination codon. The protein predicted from this region has a MW of 23,068 daltons. Based on the characteristics of the mutant Ad2ts1, which maps between coordinates 59.9 and 69.9, it is probable that the predicted protein is involved in processing of late proteins.Keywords
This publication has 20 references indexed in Scilit:
- The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNACell, 1980
- Complex splicing patterns of RNAs from the early regions of adenovirus-2Journal of Molecular Biology, 1979
- Sequence analysis of adenovirus DNAJournal of Molecular Biology, 1979
- Genetic Analysis of Adenovirus Type 2. IX. The Physical Locations of Structural GenesJournal of General Virology, 1979
- Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicingCell, 1978
- Structure of the adenovirus 2 early mRNAsCell, 1978
- The use of thin acrylamide gels for DNA sequencingFEBS Letters, 1978
- The initiation sites for RNA transcription in Ad2 DNACell, 1977
- The topography and transcription of the adenovirus genomeCell, 1977
- 3′ Non-coding region sequences in eukaryotic messenger RNANature, 1976