Heckel Plots as Indicators of Elastic Properties of Pharmaceuticals
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 12 (11-13) , 1903-1912
- https://doi.org/10.3109/03639048609042616
Abstract
In this study the usefulness of different kind of Heckel treatments to describe the elastic properties of the compressed materials was evaluated. Two methods were used to find the values for Heckel function, namely, tablet-in-die method and ejected tablets method. The slope values were calculated by means of the first derivative of the Heckel function. The reliable conclusions from the total elastic recovery were possible to obtain using the reciprocal of the difference of the Heckel upward plot slopes obtained from the two methods used-in this study. The downward part of the Heckel plot was noticed to be useful for describing the fast elasticity during the tableting process.Keywords
This publication has 1 reference indexed in Scilit:
- Compressional characteristics of four starchesJournal of Pharmacy and Pharmacology, 1983