Effects of L-Dopa and Chlorpromazine on Human Growth Hormone and TSH Secretion in Normal Subjects and Acromegalics

Abstract
Acute administration of 1 g L -dopa by mouthproduced a rise in plasma growth hormone in fasting normalsubjects: this effect was not suppressed by intravenous glucoseor by 50 mg chlorpromazine. There was no effect of L-dopaon plasma TSH.Plasma growth hormone was unaffected by L -dopa, oralglucose or chlorpromazine in 6 acromegalic patients.

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