Recovery sequence after anesthetization. II. Cyclopropane and nitrous oxide.

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Abstract
The order of the loss of certain behavioral functions with anesthetization and the order of recovery of these functions after the removal of the anesthetic were studied in white rats. The anesthetics used were cyclopropane and nitrous oxide. The following conclusions seem warranted: (1) The loss of functions proceeded in a caudo-cephalad direction. (2) The recovery proceeded in a cephalo-caudad direction. (3) The patterning of the responses was not divisible into discrete, elemental units or reflexes, the organism functioning as a totality at all times. (4) Young animals showed the same sequences as older animals, thus making more uncertain the value of the theory of myelination. (5) At present the facts are too few to warrant the acceptance of any of the common hypotheses concerning functional development although the theory of physiological gradients was supported by much of the data.

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