Response of Granular Juxtaglomerular Cells and Tissue Mast Cells in Various Experimental States

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Abstract
Mast cells, granular juxtaglomerular (j.g.) cells, and renal renin levels were studied in five different experimental conditions involving renal hypertension, DOCA hypertension, prolonged administration of NaCl in the drinking water, and treatment with compound 48/80, and dextran. The j.g. cells and mast cells behaved differently in each of these cir cumstances. A correlation between refill con tent and j.g. cells was observed. Metachro inasia could not be detected in j.g. cells and their location appeared to he unique.