Anti-IL-lα autoantibodies in patients with rheumatic diseases and in healthy subjects

Open Access

1 September 1991

journal article
Published by Oxford University Press (OUP) in Clinical and Experimental Immunology

Vol. 85 (3) , 407-412
https://doi.org/10.1111/j.1365-2249.1991.tb05740.x

Abstract

We have developed a quantitative assay for IgG autoantibodies against IL-lα using protein A-Sepharose CL-4B. We examined the autoantibodies in sera from 107 healthy subjects, 151 patients with rheumatoid arthritis (RA), 64 patients with systemic lupus erythematosus (SLE) and 16 patients with systemic sclerosis. The frequency of positive sera for the autoantibodies in patients with RA was 16.6%, which was about three times more frequent (Pin rivo.

Keywords

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