Prevention of Preterm Birth

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Abstract
Advances in the care of preterm infants have blunted what otherwise should have been a constant public outcry about the static rate of preterm birth, the leading cause of perinatal and infant morbidity and mortality in the United States. Why has the problem of prematurity not been solved? For 50 years the reply has been, to quote Eastman, “Only when the factors underlying prematurity are completely understood can any progress toward prevention be made.”1 Despite abundant new knowledge about the factors that underlie preterm birth, 8 to 9 percent of births still occur before 37 weeks' gestation, and the 1 . . .

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