Modification of Chicken Pox in Family Contacts by Administration of Gamma Globulin

Publisher Website
Google Scholar
Abstract
SINCE 1944, when the use of gamma globulin was introduced for the modification and prevention of measles,1 , 2 numerous attempts to prevent, attenuate or treat chicken pox with this agent have been reported.3 4 5 6 7 8 9 10 Before that time convalescent varicella serum had been used with similar objectives.11 In recent years, the need for a method of modification of chicken pox has become increasingly apparent, owing to the publication of descriptions of a variety of serious and sometimes fatal sequelae under certain well defined circumstances. These have included primary varicella pneumonia in adults,12 13 14 15 visceral dissemination,16 , 17 death from neonatal chicken pox,18 19 20 21 fatal chicken pox in . . .