Cyanomethyl Esters: Useful Protection for Carboxylic Acids
- 1 March 1992
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 22 (5) , 693-697
- https://doi.org/10.1080/00397919208019271
Abstract
The alkylation of carboxylate salts with chloroacetonitrile yields cyanomethyl esters. Deprotection of the carboxyl group is most readily performed by stirring with an aqueous solution of sodium sulfide.Keywords
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