Differential inhibition of ‘usual’ and ‘atypical’ serum cholinesterase by NaCl and NaF

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Abstract
SUMMARY: The inhibition of serum cholinesterase by NaCl and NaF has been studied in twelve plasmas with the ‘usual’ form of the enzyme, and in six plasmas with the ‘atypical’ form of the enzyme. Inhibition of both forms of enzyme required very much higher concentrations of NaCl than of NaF. While the ‘atypical’ enzyme was‐ more readily inhibited than the ‘usual’ enzyme with NaCl, the ‘usual’ enzyme was more readily inhibited than the ‘atypical’ enzyme with NaF. The spectrophotometer used in this investigation was purchased with a grant from the Central Research Fund, University of London.