Ontogenic development of α-adrenergic receptors and responsiveness in white adipocytes
- 15 December 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 192 (3) , 947-950
- https://doi.org/10.1042/bj1920947
Abstract
The influence of age on adipocyte alpha-adrenergic receptors was studied by using the binding of [3H]dihydroergocryptine to crude adipocyte membranes from hamsters of different ages (1-10 months). The number of alpha-receptor sites was found to increase with increasing age, but in contrast, their binding affinity remained unchanged. These changes in receptor concentrations, which were not related to cell-size differences, were also accompanied by parallel variations of the alpha-adrenergic responsiveness of the fat-cells.This publication has 21 references indexed in Scilit:
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