The effect of chemical structure on chromatographic multiple spot formation by sympathomimetic amines in the presence of hydrochloric acid

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Abstract
Of 22 sympathomimetic amines chromatographed on paper from solution in distilled water or concentrated hydrochloric acid, nine in the presence of hydrochloric acid produce multispots which are not apparent when they are chromatographed from distilled water. The presence or absence of the multiple spot phenomenon depends upon the chemical structure of each amine.