Development of a synthetic cyclized peptide derived from α‐fetoprotein that prevents the growth of human breast cancer
- 1 September 2001
- journal article
- research article
- Published by Wiley in Chemical Biology & Drug Design
- Vol. 58 (3) , 246-256
- https://doi.org/10.1034/j.1399-3011.2001.00922.x
Abstract
The peptide, EMTPVNPG, derived from alpha‐fetoprotein, inhibits estrogen‐stimulated growth of immature mouse uterus and estrogen‐dependent proliferation of human breast cancer cells. Howeve...Keywords
This publication has 30 references indexed in Scilit:
- Cyclic and linear bradykinin analogues: implications for B2antagonist designChemical Biology & Drug Design, 1999
- Solid‐state chemical stability of proteins and peptidesJournal of Pharmaceutical Sciences, 1999
- Aggregation of Recombinant Human Interferon Gamma: Kinetics and Structural TransitionsJournal of Pharmaceutical Sciences, 1998
- Rigidity of Human α-Fetoprotein Tertiary Structure Is under Ligand ControlBiochemistry, 1997
- Constitution of a biphasic insulin response to glucose in human fetal pancreatic beta-cells with glucagon-like peptide 1Journal of Clinical Endocrinology & Metabolism, 1995
- Interfacial Adsorption and Aggregation Associated Changes in Secondary Structure of Human Calcitonin Monitored by ATR-FTIR SpectroscopyBiochemistry, 1994
- Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease βA4 peptidesJournal of Molecular Biology, 1992
- Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's diseaseJournal of Molecular Biology, 1991
- Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic .beta.-protein fragmentsBiochemistry, 1990
- Stability of human interferon-ß1: oligomeric human interferon-ß1 is inactive but is reactivated by monomerizationBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1989