Increase of melanocytes around malignant melanoma
- 1 December 1975
- journal article
- Published by Springer Nature in Archives of Dermatological Research
- Vol. 252 (4) , 275-283
- https://doi.org/10.1007/bf00560367
Abstract
In split epidermal sheets with clinically normal appearance a quantitative study was carried out on dopa-positive cells in the vicinity of malignant melanomas. These data were then compared with the number of melanocytes found in the skin of the contralateral body side of the same patient. In the epidermis around superficial spreading melanoma and lentigo maligna melanoma, the number of dopa-positive cells was usually significantly higher than in the contralateral body side. On the other hand, no difference was generally found around nodular melanoma. An Epidermis-Totalpräparaten klinisch normaler Haut aus der Umgebung maligner Melanome wurde die Zahl der Melanocyten bestimmt und mit den Melanocytenwerten verglichen, die für die Epidermis der kontralateralen Körperseite des gleichen Patienten ermittelt werden konnten. In der Umgebung oberflächlich spreitender Melanome und Dubreuilh-Melanome waren die Melanocyten — verglichen mit den Werten der kontralateralen Körperseite — meist signifikant erhöht. Keine Unterschiede bestanden dagegen im allgemeinen beinodulären Melanomen.Keywords
This publication has 45 references indexed in Scilit:
- Inhibition of DNA and Protein Synthesis in Melanocytes by a Melanoma ExtractJournal of Investigative Dermatology, 1974
- Dépigmentation due à un sparadrapDermatology, 1974
- Untersuchungen zur prognostischen Bedeutung der ?Stromareaktion? beim malignen MelanomVirchows Archiv, 1973
- Bedeutung feingeweblicher Befunde für die Prognose des malignen Melanoms*Deutsche Medizinische Wochenschrift (1946), 1972
- Studies of the Melanocytes of the Epidermis Adjacent to TumorsJournal of Investigative Dermatology, 1971
- Thermodynamics of the Cold Agglutinin ReactionScandinavian Journal of Clinical and Laboratory Investigation, 1966
- The Behavior of Melanocytes in Inflammation**From the Department of Dermatology, University of Pennsylvania, School of Medicine, Philadelphia, Penna. 19104.Journal of Investigative Dermatology, 1965
- Effect of the Alpha Melanocyte Stimulating Hormone of the Pituitary on Mammalian Epidermal MelanocytesJournal of Investigative Dermatology, 1964
- Part III: General Considerations of Skin Pigmentation: Historical Background of Research on Pigmentary Diseases of the SkinJournal of Investigative Dermatology, 1959
- Quantitative and Qualitative Data on the Pigment Cells of Adult Human Epidermis1Journal of Investigative Dermatology, 1957