CARBONIC ANHYDRASE IN THE NERVOUS SYSTEM

Abstract
Thiophene-2-sulfonamide in conc. of 27 mg. % or higher had no effect on several properties and functions of the axone, the spinal cord or the cortex. Since the carbonic anhydrase of the nervous system was inhibited more than 99.99% by these concs. of the drug, it was concluded that the catalysed hydration and dehydration of CO2 were not essential functions of the nervous system.

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