Transcription of essential cell division genes is linked to chromosome replication in Escherichia coli
- 1 May 2001
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 40 (4) , 909-916
- https://doi.org/10.1046/j.1365-2958.2001.02434.x
Abstract
Cell division normally follows the completion of each round of chromosome replication in Escherichia coli. Transcription of the essential cell division genes clustered at the mra region is shown here to depend on continuing chromosomal DNA replication. After chromosome replication was blocked by either nalidixic acid treatment or thymine starvation, the transcription of these cell division genes was repressed significantly. This suggests a way in which cell division is controlled by chromosome replication.Keywords
This publication has 49 references indexed in Scilit:
- Chromosome replication and the division cycle of Escherichia coli BrPublished by Elsevier ,2004
- Co‐ordinating DNA replication with cell division in bacteria: a link between the early stages of a round of replication and mid‐cell Z ring assemblyMolecular Microbiology, 1999
- The coupling between ftsZ transcription and initiation of DNA replication is not mediated by the DnaA‐boxes upstream of ftsZ or by DnaAMolecular Microbiology, 1996
- Transcriptional regulation of ceil division genes in Escherichia coliMolecular Microbiology, 1989
- Transcription of the sulA gene and repression by LexAJournal of Molecular Biology, 1983
- An inducible DNA replication–cell division coupling mechanism in E. coliNature, 1981
- A fixed amount of chromosome replication needed for premature division septation in Bacillus subtilisJournal of Molecular Biology, 1981
- Division septation in the absence of chromosome termination in Bacillus subtilisJournal of Molecular Biology, 1979
- Effect of Thymine Concentration on the Replication Velocity of DNA in a Thymineless Mutant of Escherichia coliNature, 1970
- Relationship between Cell Size and Time of Initiation of DNA ReplicationNature, 1968