Studies in relation to biosynthesis. Part XLVI. Incorporation of cyclo-L-tryptophyl-L-proline into brevianamide A

1 January 1974

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1

p. 50-52
https://doi.org/10.1039/p19740000050

Abstract

The culture conditions and method of isolation of brevianamide A (1) from Penicillium brevicompactum have been improved. Use of ³H and ¹⁴C labelling has shown that cyclo-L-tryptophyl-L-proline (5) is incorporated efficiently into brevianamide A (1) and a biosynthetic sequence is proposed.

Keywords

PENICILLIUM
BIOSYNTHETIC
14C
EFFICIENTLY
BREVICOMPACTUM
PART XLVI
RELATION TO BIOSYNTHESIS

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