Anti-Tumour Effects of the Sesquiterpene Lactone Parthenin
- 30 April 1982
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 45 (05) , 23-27
- https://doi.org/10.1055/s-2007-971234
Abstract
The anti-tumour effects of the sesquiterpene lactone, parthenin was studied both in vivo and in vitro. Parthenin showed marked cytotoxic activity to P815 mastocytoma, L1210 leukemia, and M-1 rhabdomyosarcoma cells in vitro. In vivo studies showed intraperitoneal drug administration could either cure mice or increase their survival time after intraperitoneal of subcutaneous injection with tumour cells.Keywords
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