Highly efficient lipase-catalyzed asymmetric synthesis of chiral glycerol derivatives leading to practical synthesis of s-propranolol
- 31 December 1988
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 29 (40) , 5173-5176
- https://doi.org/10.1016/s0040-4039(00)80711-x
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- A molecular design toward biologically significant compounds based on PAF structures.Journal of Synthetic Organic Chemistry, Japan, 1987
- Asymmetric epoxidation of allyl alcohol: efficient routes to homochiral .beta.-adrenergic blocking agentsThe Journal of Organic Chemistry, 1986
- Asymmetric hydrolysis of (.+-.)-1,2-diacetoxy-3-chloropropane and its related compounds with lipase. Synthesis of optically pure (S)-propranolol.Agricultural and Biological Chemistry, 1982
- Asymmetric hydrolysis of (.+-.)-1-acetoxy-2,3-dichloropropane with enzymes and microorganisms.Agricultural and Biological Chemistry, 1982
- Total synthesis of (R)-glycerol acetonide and the antiepileptic and hypotensive drug (-)-.gamma.-amino-.beta.-hydroxybutyric acid (GABOB): use of vitamin C as a chiral starting materialJournal of the American Chemical Society, 1980
- Mode of nucleophilic addition to epichlorohydrin and related species: chiral aryloxymethyloxiranesJournal of the American Chemical Society, 1979
- Absolute configuration of glycerol derivatives. 5. Oxprenolol enantiomersThe Journal of Organic Chemistry, 1978
- LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETSThe Journal of Experimental Medicine, 1972
- .beta.-Adrenergic blocking agents. III. The optical isomers of pronethalol, propranolol, and several related compoundsJournal of Medicinal Chemistry, 1968
- Optical Isomers of PropranololNature, 1966