The early history of scleroderma is confused with that of leprosy, ichthyosis and keloid. Under the name of ichthyosis corii, Curzio,1in 1752, described a case which was probably diffuse scleroderma. Alibert2and Addison,3under the name of true keloid, distinguished the localized form of scleroderma from false keloid, the latter being what is now called keloid. Henke4described the infantile form of the disease clearly and in a footnote gave a typical case of the diffuse type in the adult. He called it Verhaertung des Zellgewebes or induratio telae cellularis. Fagge5reported an interesting postmortem examination of the skin and liver in a case of diffuse "scleriasis." T. C. Fox6gave an interesting account of the early history of the disease. In 1895, Lewin and Heller7reviewed the whole subject up to that date, collecting reports of more than 500 cases from