Late pulmonary response in guinea pigs after ascaris challenge.
- 1 January 1985
- journal article
- research article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 146 (1) , 121-122
- https://doi.org/10.1620/tjem.146.121
Abstract
TAKISHIMA, T., YAMAUCHI, K., ISHII, M., CHAO, C.-L., IIJIMA, H., SHIMURA, S., SHINDOH, Y., INOUE, H. and MUE, S. Late Pulmonary Response in Guinea Pigs after Ascaris Challenge. Tohoku J. exp. Med., 1985, 146 (1), 121-122-Respiratory resistance of guinea pigs immunized with Ascaris suum was measured over 6hr after aerosol challenge of the allergen by use of the oscillation method. These animals showed a biphasic pulmonary response to the aerosol challenge with Ascaris suum. Histological analysis of these animals revealed a narrowing of bronchial lumen, peribronchial edema and neutrophil-rich mucous in bronchial lumen at the late pulmonary response.Keywords
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