Synthesis and assay for activity of a proposed anorexogenic agent, L-pyroglutamyl-L-histidyl-glycine
- 1 January 1981
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 59 (1) , 88-90
- https://doi.org/10.1139/y81-015
Abstract
L-Pyroglutamyl-L-histidyl-glycine has been reported to be an anorexogenic agent in female mice. In this report the synthesis of this tripeptide is described. The synthetic material was injected into female and male mice and into male rats. In no instance did the animals decrease their food intake. Further, the weights of peptide-treated animals were the same as those of control (saline-treated) animals. The results suggest that L-pyroglutamyl-L-histidyl-glycine is not an anorexogenic agent.This publication has 4 references indexed in Scilit:
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