The Electrolyte and Protein Concentration in Hypertonic Glucose Solutions 15 Minutes after Intra-Intestinal Injection into Small Intestinal Sections of Varying Lengths

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Abstract
Experimental examination of hypertonic glucose solutions injected into small intestinal sections from live pigs and aspirated 15 minutes later showed: The volume of a hypertonic glucose solution increases parallel with increasing length of the section of the jejunum into which the solution is diffused. The amount of sodium and chloride seeping in with the water during the experimental 15-minute-periods is equal to the rise in volume and thus the amounts of sodium and chloride seeping in vary with the size of the area of the mucous membrane on which the 50 ml of a 50% glucose solution is diffused. Not only the amount but also the concentration of sodium and chloride in the aspirates increases considerably when the intestinal sections are prolonged from 100 to 200 cm. A further prolongation rather impedes the increase in concentration. The volume, i.e. the sodium and chloride content of the transuded fluid, is uniform in at least six successive experiments in which the same intestinal section is exposed. The valuation of results from the K analyses cannot be quite as clear-cut, probably because of a certain admixture of blood corpuscles. The protein concentration rises in the fluid in the intestinal lumen and a pronounced edema of the intestinal wall and the mesentery is noted.

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